By Tiago G Fernandes, Maria Margarida Diogo
Stem phone bioprocessing describes the most large-scale bioprocessing techniques for either stem phone tradition and purification, envisaging the applying of those cells for regenerative medication and drug screening. Bioreactor configurations are defined, together with their purposes for stem cellphone growth, and stem cellphone separation strategies equivalent to isolation and purification are mentioned. uncomplicated definitions are supplied in regards to the types of stem cells, from grownup stem cells to the more moderen prompted pluripotent stem cells. the most features of those diversified stem telephone varieties are defined, along the molecular mechanisms underlying their self-renewal and differentiation. The e-book additionally makes a speciality of methodologies presently used for in vitro stem mobile tradition below static stipulations, together with the problem of xeno-free tradition stipulations, in addition to tradition parameters that effect stem phone tradition. methods for either stem mobile tradition and separation in micro-scale stipulations are provided, together with using mobile microarrays for high-throughput screening of the impact of either soluble and extracellular matrix molecules. a different part is devoted to software of stem cells for regenerative medicine.
- Maintains a different specialize in either the fundamental stem mobilephone biology techniques, and their translation to large-scale bioprocessing approaches
- Envisages using stem cells in regenerative drugs and drug screening applications
- Discusses the appliance of microscale innovations as a device to accomplish simple stem telephone biology studies
Read Online or Download Stem Cell Bioprocessing: For Cellular Therapy, Diagnostics and Drug Development (Woodhead Publishing Series in Biomedicine) PDF
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Extra resources for Stem Cell Bioprocessing: For Cellular Therapy, Diagnostics and Drug Development (Woodhead Publishing Series in Biomedicine)
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